Chronic Inflammation

Chronic Low-grade Inflammation after Exercise: Controversies

chronic low-grade inflammation after exercise: controversies

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TLRs and chronic inflammation.

After the discovery of Toll-like receptors (TLRs), innate immune mechanisms came back in the focus of scientific research. With more and more mechanisms of TLR biology known, it has become clear that these and also other innate immune receptors are not only of crucial importance in the immune response to invading pathogens, but also play a role in the homeostasis of commensal flora and in the r...

Chronic inflammation in asthma

It is now widely accepted that chronic airway inflammation plays a key role in asthma [1]. This fundamental feature has been included in the most recent definitions of the disease: hence the Global Strategy for Asthma Management and Prevention reports that "asthma is a chronic inflammatory disease of the airways in which many cell types play a role, in particular mast cells, eosinophils and T-l...

Inflammation in Chronic Wounds

Non-healing chronic wounds present a major biological, psychological, social, and financial burden on both individual patients and the broader health system. Pathologically extensive inflammation plays a major role in the disruption of the normal healing cascade. The causes of chronic wounds (venous, arterial, pressure, and diabetic ulcers) can be examined through a juxtaposition of normal heal...